Product Name :
beta Tubulin Mouse Monoclonal Antibody [1-B11]

Predicted band size :
50 kDa

Observed band size :
50 kDa

Synonyms:
Beta 4 tubulin antibody Beta 5 tubulin antibody BetaTubulin antibody TBB5_HUMAN antibody TUBB antibody TUBB2 antibody TUBB2A antibody TUBB5 antibody tubulin beta 2A antibody Tubulin beta chain antibody 展开

Function :
Tubulin in molecular biology can refer either to the tubulin protein superfamily of globular proteins, or one of the member proteins of that superfamily. α- and β-tubulins polymerize into microtubules, a major component of the eukaryotic cytoskeleton. Microtubules function in many essential cellular processes, including mitosis. Tubulin-binding drugs kill cancerous cells by inhibiting microtubule dynamics, which are required for DNA segregation and therefore cell division. In eukaryotes, there are six members of the tubulin superfamily, although not all are present in all species. Both α and β tubulins have a mass of around 50 kDa and are thus in a similar range compared to actin (with a mass of ~42 kDa). In contrast, tubulin polymers (microtubules) tend to be much bigger than actin filaments due to their cylindrical nature. Tubulin was long thought to be specific to eukaryotes.Deruxtecan manufacturer More recently, however, several prokaryotic proteins have been shown to be related to tubulin.BuyBenzene-1,2,4,5-tetraol

Antibody Type:
Mouse Monoclonal Antibody

Immunogen :
Synthetic peptide within human Beta tubulin aa 51-100.PMID:33435806

Species reactivity:
Human, Mouse, Rat, Zebrafish

Verify application:
WB, IF-Cell, IHC-P, FC, IF-Tissue

Coupling :
unconjugated

Clone number:
1-B11

RRID:
AB_2819165

Form :
Liquid

Concentration :
2ug/ul

Storage instructions:
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.

Storage buffer solution:
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Subtype:
IgG1

Purification method :
Protein A affinity purified.

ELTSA :

Molecular weight :
Predicted band size: 50 kDa

Positive control :
K-562 cell lysate, Jurkat cell lysate, HeLa cell lysate, NIH/3T3 cell lysate, RAW264.7 cell lysate, C6 cell lysate, Hela, HepG2, NIH/3T3, mouse brain tissue, hybrid fish (crucian-carp) brain tissue lysates.