Product Name :
RND3 Mouse Monoclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
ARHE antibody memB antibody Protein MemB antibody Ras homolog gene family member E antibody Rho family GTPase 3 antibody Rho-related GTP-binding protein Rho8 antibody Rho-related GTP-binding protein RhoE antibody Rho8 antibody RhoE antibody Rnd3 antibody 展开
Function :
The Ras p21 family of guanine nucleotide proteins has been widely studied in view of its apparent role in signal transduction pathways and high frequency of mutations in human malignancies. It is now clear, however, that the Ras proteins (H-, K- and N-Ras p21) are members of a much larger superfamily of related proteins. Six members of this family, Rap 1A, Rap 1B, Rap 2, R-Ras, Ral A and Ral B, exhibit approximately 50% amino acid homology to Ras. The six mammalian Rho proteins (Rho A, B, C, G, 7 and 8) are approximately 30% homologous to Ras and are expressed in a wide range of cell types. Both Ras p21 and Rho p21, as well as other members of the Ras superfamily, contain a carboxy-terminal CAAX sequence (C, cysteine; A, aliphatic amino acid; X, any amino acid) which in the case of Ras has been shown to be essential for correct localization and function.
Antibody Type:
Mouse Monoclonal Antibody
Immunogen :
Recombinant protein
Species reactivity:
Human
Verify application:
WB, ICC, IHC-P, FC
Coupling :
unconjugated
Clone number:
RRID:
Form :
Liquid
Concentration :
2ug/ul
Storage instructions:
4℃; -20℃ for long term storage.1272758-17-4 Chemscene
Storage buffer solution:
Purified antibody in PBS with 0.Price of 529476-80-0 05% sodium azide.PMID:33381984
Subtype:
IgG1
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
27 kDa
Positive control :
Human RND3 recombinant protein, RND3-hIgGFc transfected HEK293 cell lysate, Hela, human bladder cancer tissue.