Product Name :
PDK1 Recombinant Rabbit Monoclonal Antibody [JA67-30]
Predicted band size :
49 kDa
Observed band size :
46 kDa
Synonyms:
[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial antibody HGNC:8809 antibody Mitochondrial pyruvate dehydrogenase kinase isoenzyme 1 antibody PDH kinase 1 antibody Pdk1 antibody PDK1_HUMAN antibody Pyruvate dehydrogenase kinase isoform 1 antibody Pyruvate dehydrogenase kinase, isoenzyme 1 antibody
Function :
Mitochondrial pyruvate dehydrogenase (PDH) catalyzes the oxidative decarboxylation of pyruvate and plays a central role in the regulation of homeostasis of carbohydrate fuels in mammals. PDH activity is controlled by a phosphorylation/dephosphorylation cycle, phosphorylation leading to inactivation and dephosphorylation leading to reactivation of PDH. The phosphorylation of PDH is catalyzed by pyruvate dehydrogenase kinase (PDK), the activity of which is stimulated by the products of PDH catalysis.1,2-Dicarbadodecaborane(12) web PDK1 consists of alpha and beta subunits; the kinase activity resides in the alpha subunit.1394346-20-3 Order Three PDK isoenzymes have been identified in humans (PDK1, 2 and 3) and two have been identified in rodent (PDK1 and 2).
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Synthetic peptide within Human PDK1 aa 16-65 / 436.PMID:33506687
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, IHC-P, IP, FC, IF-Cell, IF-Tissue
Coupling :
unconjugated
Clone number:
JA67-30
RRID:
AB_3070512
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 49 kDa
Positive control :
Mouse heart tissue lysate, rat heart tissue lysate, Hela, NIH/3T3, mouse heart tissue, rat heart tissue.