Product Name :
c-Fos Recombinant Rabbit Monoclonal Antibody [JJ0938]
Predicted band size :
Observed band size :
Synonyms:
Activator protein 1 antibody AP 1 antibody C FOS antibody Cellular oncogene c fos antibody Cellular oncogene fos antibody FBJ murine osteosarcoma viral (v fos) oncogene homolog (oncogene FOS) antibody FBJ murine osteosarcoma viral oncogene homolog antibody FBJ murine osteosarcoma viral v fos oncogene homolog antibody FBJ Osteosarcoma Virus antibody FOS antibody 展开
Function :
Protein c-Fos is a proto-oncogene that is the human homolog of the retroviral oncogene v-fos.Cubane-1-carboxylic acid manufacturer [5] It is encoded in humans by the FOS gene. It was first discovered in rat fibroblasts as the transforming gene of the FBJ MSV (Finkel–Biskis–Jinkins murine osteogenic sarcoma virus) (Curran and Tech, 1982). It is a part of a bigger Fos family of transcription factors which includes c-Fos, FosB, Fra-1 and Fra-2.It has been mapped to chromosome region 14q21→q31. c-Fos encodes a 62 kDa protein, which forms heterodimer with c-jun (part of Jun family of transcription factors), resulting in the formation of AP-1 (Activator Protein-1) complex which binds DNA at AP-1 specific sites at the promoter and enhancer regions of target genes and converts extracellular signals into changes of gene expression.Price of 2169908-22-7 It plays an important role in many cellular functions and has been found to be overexpressed in a variety of cancers.PMID:33580389
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Synthetic peptide within Human c-Fos aa 231-268 / 380.
Species reactivity:
Mouse, Human, Rat
Verify application:
WB, IHC-P, FC, IF-Cell
Coupling :
unconjugated
Clone number:
JJ0938
RRID:
AB_3070261
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
41 kDa
Positive control :
Human placenta tissue, NIH/3T3, NIH/3T3 cell lysate, MCF-7 cell lysate, HeLa serum starved for 40 hours then treated with 20% FBS for 2 hours.