Product Name :
TGFBR3 Mouse Monoclonal Antibody [H11-C5]
Predicted band size :
Observed band size :
Synonyms:
Beta glycan antibody Betaglycan antibody Betaglycan proteoglycan antibody BGCAN antibody TGBR3_HUMAN antibody TGF beta receptor type 3 antibody TGF beta receptor type III antibody TGF-beta receptor type 3 antibody TGF-beta receptor type III antibody TGFB R3 antibody 展开
Function :
A total of three members of the TGFβ family, TGFβ1, TGFβ2 and TGFβ3, have been identified in mammals. Each is synthesized as a latent precursor that is subsequently cleaved forming the 112 amino acid growth factor which becomes active upon dimerization. TGFβs mediate their activity by high affinity binding to the type II receptor transmembrane protein with a cytoplasmic serine-threonine kinase domain. TGFβ RIII (transforming growth factor beta receptor type 3), also known as TGFBR3 or TGFR-3, is an 850 amino acid secreted and single-pass type I membrane protein that contains one ZP domain and may assist in capturing TGFβ for presentation to signaling receptors. TGFβ RIII undergoes post-translational modification by glycosaminoglycan groups (GAG) and is encoded by a gene that maps to human chromosome 1p22.2.
Antibody Type:
Mouse Monoclonal Antibody
Immunogen :
Recombinant protein
Species reactivity:
Human, Mouse
Verify application:
WB
Coupling :
unconjugated
Clone number:
H11-C5
RRID:
Form :
Liquid
Concentration :
2ug/ul
Storage instructions:
4℃; -20℃ for long term storage.(4-(3-Hydroxypropyl)phenyl)boronic acid web
Storage buffer solution:
Purified antibody in PBS with 0.(R)-1-(2-Methoxypyridin-4-yl)ethanamine Chemscene 05% sodium azide.PMID:33530837
Subtype:
IgG2b
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
93 kDa
Positive control :
Human TGFBR3 recombinant protein, Jurkat, HeLa, MCF-7, F9, SK-N-SH, NIH3T3 cell lysate.