Product Name :
PINK1 Rabbit Polyclonal Antibody
Predicted band size :
63 kDa
Observed band size :
63 kDa
Synonyms:
BRPK antibody FLJ27236 antibody mitochondrial antibody PARK 6 antibody PARK6 antibody Phosphatase and Tensin Homolog antibody PINK 1 antibody PINK1 antibody PINK1_HUMAN antibody Protein kinase BRPK antibody 展开
Function :
A member of the serine / threonine protein kinase family, PTEN induced putative kinase 1 (PINK1) is a tumor suppressor. PINK1 is primarily located in mitochondria, and is ubiquitously expressed in testis, skeletal muscle, and heart tissue. at lower levels in pancreas, ovary, brain, placenta, kidney, liver, prostate and small intestine. During cellular stress PINK1 protects against mitochondrial dysfunction by inducing phosphorylation mitochondrial proteins.Formula of 41203-22-9 PINK1 mutations may give rise to different autophosphorylation activity.Benzo[d]oxazole-7-carbaldehyde In stock Mutations in the PINK1 gene (PARK6) are associated with early onset Parkinson’s disease, a recessive neurodegenerative disorder characterized by resting tremor, muscular rigidity, bradykinesia and postural instability. Parkinson’s disease generally involves the presence of intraneuronal accumulations of aggregated proteins (Lewy bodies) in brain neurons.
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
Recombinant protein within Human PINK1 aa 94-581 / 581.PMID:33507266
Species reactivity:
Human
Verify application:
WB
Coupling :
unconjugated
Clone number:
RRID:
AB_3069043
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
Storage buffer solution:
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Immunogen affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 63 kDa
Positive control :
HeLa treated with 10μM CCCP for 24 hours cell lysate.